Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma

Hepatocyte growth factor (HGF) signaling through its receptor Met has been implicated in hepatocellular carcinoma tumorigenesis and progression. Met interaction with integrins is shown to modulate the downstream signaling to Akt and ERK (extracellular-regulated kinase). In this study, we developed a...

Descripción completa

Detalles Bibliográficos
Autores principales: Jafarnejad, Mohammad, Sové, Richard J., Danilova, Ludmila, Mirando, Adam C., Zhang, Yu, Yarchoan, Mark, Tran, Phuoc T., Pandey, Niranjan B., Fertig, Elana J., Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697704/
https://www.ncbi.nlm.nih.gov/pubmed/31452933
http://dx.doi.org/10.1038/s41540-019-0107-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697704/
https://www.ncbi.nlm.nih.gov/pubmed/31452933
http://dx.doi.org/10.1038/s41540-019-0107-2

Ejemplares similares