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Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma
Hepatocyte growth factor (HGF) signaling through its receptor Met has been implicated in hepatocellular carcinoma tumorigenesis and progression. Met interaction with integrins is shown to modulate the downstream signaling to Akt and ERK (extracellular-regulated kinase). In this study, we developed a...
Autores principales: | Jafarnejad, Mohammad, Sové, Richard J., Danilova, Ludmila, Mirando, Adam C., Zhang, Yu, Yarchoan, Mark, Tran, Phuoc T., Pandey, Niranjan B., Fertig, Elana J., Popel, Aleksander S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697704/ https://www.ncbi.nlm.nih.gov/pubmed/31452933 http://dx.doi.org/10.1038/s41540-019-0107-2 |
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