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A linear mixed model approach to gene expression-tumor aneuploidy association studies

Aneuploidy, defined as abnormal chromosome number or somatic DNA copy number, is a characteristic of many aggressive tumors and is thought to drive tumorigenesis. Gene expression-aneuploidy association studies have previously been conducted to explore cellular mechanisms associated with aneuploidy....

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Detalles Bibliográficos
Autores principales: Yao, Douglas W., Balanis, Nikolas G., Eskin, Eleazar, Graeber, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697733/
https://www.ncbi.nlm.nih.gov/pubmed/31420589
http://dx.doi.org/10.1038/s41598-019-48302-1