Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4(+) T Cells

CD4(+) T cells are essential for immune protection against viruses, yet their multiple roles remain ill-defined at the single-cell level in humans. Using HLA class II tetramers, we studied the functional properties and clonotypic architecture of EBV-specific CD4(+) T cells in patients with infectiou...

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Detalles Bibliográficos
Autores principales: Meckiff, Benjamin J., Ladell, Kristin, McLaren, James E., Ryan, Gordon B., Leese, Alison M., James, Eddie A., Price, David A., Long, Heather M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2019
Materias:
Infectious Disease and Host Response
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697742/
https://www.ncbi.nlm.nih.gov/pubmed/31308093
http://dx.doi.org/10.4049/jimmunol.1900377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697742/
https://www.ncbi.nlm.nih.gov/pubmed/31308093
http://dx.doi.org/10.4049/jimmunol.1900377

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