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High-speed AFM reveals subsecond dynamics of cardiac thin filaments upon Ca(2+) activation and heavy meromyosin binding
High-speed atomic force microscopy (HS-AFM) can be used to study dynamic processes with real-time imaging of molecules within 1- to 5-nm spatial resolution. In the current study, we evaluated the 3-state model of activation of cardiac thin filaments (cTFs) isolated as a complex and deposited on a mi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697793/ https://www.ncbi.nlm.nih.gov/pubmed/31358631 http://dx.doi.org/10.1073/pnas.1903228116 |