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High-speed AFM reveals subsecond dynamics of cardiac thin filaments upon Ca(2+) activation and heavy meromyosin binding

High-speed atomic force microscopy (HS-AFM) can be used to study dynamic processes with real-time imaging of molecules within 1- to 5-nm spatial resolution. In the current study, we evaluated the 3-state model of activation of cardiac thin filaments (cTFs) isolated as a complex and deposited on a mi...

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Detalles Bibliográficos
Autores principales: Matusovsky, Oleg S., Mansson, Alf, Persson, Malin, Cheng, Yu-Shu, Rassier, Dilson E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697793/
https://www.ncbi.nlm.nih.gov/pubmed/31358631
http://dx.doi.org/10.1073/pnas.1903228116