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TMEM203 is a binding partner and regulator of STING-mediated inflammatory signaling in macrophages

Regulation of IFN signaling is critical in host recognition and response to pathogens while its dysregulation underlies the pathogenesis of several chronic diseases. STimulator of IFN Genes (STING) has been identified as a critical mediator of IFN inducing innate immune pathways, but little is known...

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Detalles Bibliográficos
Autores principales: Li, Yang, James, Sharmy J., Wyllie, David H., Wynne, Claire, Czibula, Agnes, Bukhari, Ahmed, Pye, Katherine, Bte Mustafah, Seri Musfirah, Fajka-Boja, Roberta, Szabo, Eniko, Angyal, Adrienn, Hegedus, Zoltan, Kovacs, Laszlo, Hill, Adrian V. S., Jefferies, Caroline A., Wilson, Heather L., Yongliang, Zhang, Kiss-Toth, Endre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697806/
https://www.ncbi.nlm.nih.gov/pubmed/31346090
http://dx.doi.org/10.1073/pnas.1901090116