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Meiotic viral attenuation through an ancestral apoptotic pathway

The programmed release of apoptogenic proteins from mitochondria is a core event of apoptosis, although ancestral roles of this phenomenon are not known. In mammals, one such apoptogenic protein is Endonuclease G (EndoG), a conserved mitochondrial nuclease that fragments the DNA of dying cells. In t...

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Detalles Bibliográficos
Autores principales: Gao, Jie, Chau, Sabrina, Chowdhury, Fuad, Zhou, Tina, Hossain, Saif, McQuibban, G. Angus, Meneghini, Marc D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697816/
https://www.ncbi.nlm.nih.gov/pubmed/31266891
http://dx.doi.org/10.1073/pnas.1900751116