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A Study on Merits and Demerits of Two Main Gene Silencing Techniques in Mice

BACKGROUND: Transgenic mice are being considered as invaluable tool in biological sciences towards comprehension of the cause of the genetic diseases. Manipulated embryonic stem (ES) cells are used to produce loss-of-function mutant mice. Microinjection of manipulated ES cells into blastocoel cavity...

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Detalles Bibliográficos
Autores principales: Khezri, Jafar, Heidari, Farid, Shamsara, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697828/
https://www.ncbi.nlm.nih.gov/pubmed/31457022
http://dx.doi.org/10.15171/ijb.1632