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A Study on Merits and Demerits of Two Main Gene Silencing Techniques in Mice
BACKGROUND: Transgenic mice are being considered as invaluable tool in biological sciences towards comprehension of the cause of the genetic diseases. Manipulated embryonic stem (ES) cells are used to produce loss-of-function mutant mice. Microinjection of manipulated ES cells into blastocoel cavity...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Institute of Genetic Engineering and Biotechnology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697828/ https://www.ncbi.nlm.nih.gov/pubmed/31457022 http://dx.doi.org/10.15171/ijb.1632 |