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Decline of COPD exacerbations in clinical trials over two decades – a systematic review and meta-regression

BACKGROUND: An important goal of chronic obstructive pulmonary disease (COPD) treatment is to reduce the frequency of exacerbations. Some observations suggest a decline in exacerbation rates in clinical trials over time. A more systematic understanding would help to improve the design and interpreta...

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Detalles Bibliográficos
Autores principales: Andreas, Stefan, Röver, Christian, Heinz, Judith, Straube, Sebastian, Watz, Henrik, Friede, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697937/
https://www.ncbi.nlm.nih.gov/pubmed/31420040
http://dx.doi.org/10.1186/s12931-019-1163-2