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Decline of COPD exacerbations in clinical trials over two decades – a systematic review and meta-regression
BACKGROUND: An important goal of chronic obstructive pulmonary disease (COPD) treatment is to reduce the frequency of exacerbations. Some observations suggest a decline in exacerbation rates in clinical trials over time. A more systematic understanding would help to improve the design and interpreta...
Autores principales: | Andreas, Stefan, Röver, Christian, Heinz, Judith, Straube, Sebastian, Watz, Henrik, Friede, Tim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697937/ https://www.ncbi.nlm.nih.gov/pubmed/31420040 http://dx.doi.org/10.1186/s12931-019-1163-2 |
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