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miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt–β-catenin pathway
BACKGROUND: MicroRNAs (miRNAs) play crucial roles in tumor initiation and development. Previously, we indicated that miR-504 is downregulated and suppresses tumor proliferation in glioblastoma (GBM). However, the regulation and relevant mechanism of miR-504 in GBM mesenchymal (ME) transition remain...
Autores principales: | Liu, Qiang, Guan, Yanlei, Li, Zhenhang, Wang, Yao, Liu, Yu, Cui, Run, Wang, Yunjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697940/ https://www.ncbi.nlm.nih.gov/pubmed/31419987 http://dx.doi.org/10.1186/s13046-019-1370-1 |
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