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Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum

BACKGROUND: Severe malarial anemia (SMA) is a leading cause of malaria-related morbidity and mortality in children. The genetic factors that influence development of SMA and inefficient erythropoiesis, a central pathogenic feature of SMA, are only partially understood. METHODS: We performed a pilot...

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Detalles Bibliográficos
Autores principales: Kisia, Lily E., Kempaiah, Prakasha, Anyona, Samuel B., Munde, Elly O., Achieng, Angela O., Ong’echa, John M., Lambert, Christophe G., Chelimo, Kiprotich, Ouma, Collins, Perkins , Douglas J., Raballah, Evans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698010/
https://www.ncbi.nlm.nih.gov/pubmed/31420016
http://dx.doi.org/10.1186/s12881-019-0866-z