eIF2α promotes vascular remodeling via autophagy in monocrotaline-induced pulmonary arterial hypertension rats

PURPOSE: Eukaryotic initiation factor 2α (eIF2α) plays important roles in the proliferation and survival of pulmonary artery smooth muscle cells (PASMCs) in animal hypoxia-induced pulmonary hypertension models. However, the underlying mechanism remains unknown at large. Autophagy has been reported t...

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Detalles Bibliográficos
Autores principales: Guo, Linya, Li, Yanbing, Tian, Ying, Gong, Shaoxin, Chen, Xi, Peng, Tianhong, Wang, Aiping, Jiang, Zhisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698179/
https://www.ncbi.nlm.nih.gov/pubmed/31496656
http://dx.doi.org/10.2147/DDDT.S213817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698179/
https://www.ncbi.nlm.nih.gov/pubmed/31496656
http://dx.doi.org/10.2147/DDDT.S213817

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