Cargando…

eIF2α promotes vascular remodeling via autophagy in monocrotaline-induced pulmonary arterial hypertension rats

PURPOSE: Eukaryotic initiation factor 2α (eIF2α) plays important roles in the proliferation and survival of pulmonary artery smooth muscle cells (PASMCs) in animal hypoxia-induced pulmonary hypertension models. However, the underlying mechanism remains unknown at large. Autophagy has been reported t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Linya, Li, Yanbing, Tian, Ying, Gong, Shaoxin, Chen, Xi, Peng, Tianhong, Wang, Aiping, Jiang, Zhisheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698179/ https://www.ncbi.nlm.nih.gov/pubmed/31496656 http://dx.doi.org/10.2147/DDDT.S213817

Ejemplares similares

Formononetin attenuates monocrotaline-induced pulmonary arterial hypertension via inhibiting pulmonary vascular remodeling in rats
por: Cai, Changhong, et al.
Publicado: (2019)

Shikonin improves pulmonary vascular remodeling in monocrotaline‑induced pulmonary arterial hypertension via regulation of PKM2
por: Li, Wenfeng, et al.
Publicado: (2023)

Astragaloside IV blocks monocrotaline-induced pulmonary arterial hypertension by improving inflammation and pulmonary artery remodeling
por: Jin, Haifeng, et al.
Publicado: (2021)

Hypoxic pulmonary vasoconstriction and vascular contractility in monocrotaline-induced pulmonary arterial hypertensive rats
por: Kim, Hae Jin, et al.
Publicado: (2016)

Nicorandil Attenuates Monocrotaline-Induced Vascular Endothelial Damage and Pulmonary Arterial Hypertension
por: Sahara, Makoto, et al.
Publicado: (2012)

Glycyrrhizin, inhibitor of high mobility group box-1, attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling in rats
por: Yang, Pil-Sung, et al.
Publicado: (2014)

Farnesyl diphosphate synthase regulated endothelial proliferation and autophagy during rat pulmonary arterial hypertension induced by monocrotaline
por: Jin, Tingting, et al.
Publicado: (2022)

Exercise preconditioning prevents left ventricular dysfunction and remodeling in monocrotaline-induced pulmonary hypertension
por: Schmidt, Cristine, et al.
Publicado: (2020)

Effects of renal denervation on monocrotaline induced pulmonary remodeling
por: Liu, Qian, et al.
Publicado: (2017)

Erratum to: Glycyrrhizin, inhibitor of high mobility group box-1, attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling in rats
por: Yang, Pil-Sung, et al.
Publicado: (2016)

Simvastatin, Sildenafil and Their Combination in Monocrotaline Induced Pulmonary Arterial Hypertension
por: Lee, Dong Seok, et al.
Publicado: (2010)

Maprotiline Prevents Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats
por: Tong, Yi, et al.
Publicado: (2018)

Arctigenin prevents monocrotaline-induced pulmonary arterial hypertension in rats
por: Jiang, Wei-Long, et al.
Publicado: (2019)

Dapagliflozin, sildenafil and their combination in monocrotaline-induced pulmonary arterial hypertension
por: Tang, Yi, et al.
Publicado: (2022)

Notopterol Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rat
por: Huang, Lin, et al.
Publicado: (2022)

Activation of AMPK Prevents Monocrotaline-Induced Extracellular Matrix Remodeling of Pulmonary Artery
por: Li, Shaojun, et al.
Publicado: (2016)

Postpartum pulmonary circulation in pregnant rats with monocrotaline-induced pulmonary arterial hypertension
por: Jing, He, et al.
Publicado: (2020)

Calorie Restriction Attenuates Monocrotaline-induced Pulmonary Arterial Hypertension in Rats
por: Ding, Mingge, et al.
Publicado: (2015)

Inhibitory effects of formononetin on the monocrotaline-induced pulmonary arterial hypertension in rats
por: Wu, Yonghui, et al.
Publicado: (2020)

Right Ventricle Remodeling Metabolic Signature in Experimental Pulmonary Hypertension Models of Chronic Hypoxia and Monocrotaline Exposure
por: Hautbergue, Thaïs, et al.
Publicado: (2021)

Lodenafil treatment in the monocrotaline model of pulmonary hypertension in rats
por: Polonio, Igor Bastos, et al.
Publicado: (2014)

Arginase Inhibition Reverses Monocrotaline-Induced Pulmonary Hypertension
por: Jung, Christian, et al.
Publicado: (2017)

Cannabidiol Ameliorates Monocrotaline-Induced Pulmonary Hypertension in Rats
por: Sadowska, Olga, et al.
Publicado: (2020)

Stage-dependent changes of β2-adrenergic receptor signaling in right ventricular remodeling in monocrotaline-induced pulmonary arterial hypertension
por: Sun, Fengjiao, et al.
Publicado: (2018)

Decreased Expression of Canstatin in Rat Model of Monocrotaline-Induced Pulmonary Arterial Hypertension: Protective Effect of Canstatin on Right Ventricular Remodeling
por: Sugiyama, Akira, et al.
Publicado: (2020)

Resveratrol Prevents Right Ventricle Remodeling and Dysfunction in Monocrotaline-Induced Pulmonary Arterial Hypertension with a Limited Improvement in the Lung Vasculature
por: Vázquez-Garza, Eduardo, et al.
Publicado: (2020)

Matrix metalloproteinases are possible targets in monocrotaline-induced pulmonary hypertension: investigation of anti-remodeling effects of alagebrium and everolimus
por: Atlı, Özlem, et al.
Publicado: (2017)

Calorie Restriction Attenuates Monocrotaline-induced Pulmonary Arterial Hypertension in Rats: Erratum
Publicado: (2015)

Inhibition of Shp2 ameliorates monocrotaline-induced pulmonary arterial hypertension in rats
por: Cheng, Yusheng, et al.
Publicado: (2018)

Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats
por: Dahal, Bhola K, et al.
Publicado: (2011)

Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension
por: Kosanovic, Djuro, et al.
Publicado: (2011)

Quercetin attenuates the progression of monocrotaline-induced pulmonary hypertension in rats
por: Gao, Hanhua, et al.
Publicado: (2012)

The Beneficial Effect of Suramin on Monocrotaline-Induced Pulmonary Hypertension in Rats
por: Izikki, Mohamed, et al.
Publicado: (2013)

Magnesium Sulfate Mitigates the Progression of Monocrotaline Pulmonary Hypertension in Rats
por: Chang, Chao-Yuan, et al.
Publicado: (2019)

The protective role of EP300 in monocrotaline-induced pulmonary hypertension
por: Yang, Lei, et al.
Publicado: (2023)

Sodium Selenite Attenuates Balloon Injury-Induced and Monocrotaline-Induced Vascular Remodeling in Rats
por: Cai, Changhong, et al.
Publicado: (2021)

Pulmonary Vascular Remodeling in Pulmonary Hypertension
por: Jia, Zhuangzhuang, et al.
Publicado: (2023)

Pulmonary vessel casting in a rat model of monocrotaline-mediated pulmonary hypertension
por: Zhu, Zhongkai, et al.
Publicado: (2020)

Therapeutic Benefits of Induced Pluripotent Stem Cells in Monocrotaline-Induced Pulmonary Arterial Hypertension
por: Huang, Wei-Chun, et al.
Publicado: (2016)

Hydroxysafflor yellow A improves established monocrotaline-induced pulmonary arterial hypertension in rats
por: Han, Xiaotong, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_8u542m0kpkqava0q34d55t7h8g