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MicroRNA-200b and microRNA-200c are up-regulated in PCOS granulosa cell and inhibit KGN cell proliferation via targeting PTEN

BACKGROUND: Polycystic ovary syndrome (PCOS) is one of the most common endocrine metabolic disorders characterized by hyperandrogenism, polycystic ovaries and ovulatory dysfunction. Several studies have reported that the aberrant expression of miRNAs contributes a lot to disordered folliculogenesis...

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Detalles Bibliográficos
Autores principales: He, Tingting, Sun, Yifei, Zhang, Yingchun, Zhao, Shigang, Zheng, Yanjun, Hao, Guimin, Shi, Yuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698342/
https://www.ncbi.nlm.nih.gov/pubmed/31421682
http://dx.doi.org/10.1186/s12958-019-0505-8