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MicroRNA-200b and microRNA-200c are up-regulated in PCOS granulosa cell and inhibit KGN cell proliferation via targeting PTEN
BACKGROUND: Polycystic ovary syndrome (PCOS) is one of the most common endocrine metabolic disorders characterized by hyperandrogenism, polycystic ovaries and ovulatory dysfunction. Several studies have reported that the aberrant expression of miRNAs contributes a lot to disordered folliculogenesis...
Autores principales: | He, Tingting, Sun, Yifei, Zhang, Yingchun, Zhao, Shigang, Zheng, Yanjun, Hao, Guimin, Shi, Yuhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698342/ https://www.ncbi.nlm.nih.gov/pubmed/31421682 http://dx.doi.org/10.1186/s12958-019-0505-8 |
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