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Ferroportin downregulation promotes cell proliferation by modulating the Nrf2–miR-17-5p axis in multiple myeloma

Recent findings demonstrate that aberrant downregulation of the iron-exporter protein, ferroportin (FPN1), is associated with poor prognosis and osteoclast differentiation in multiple myeloma (MM). Here, we show that FPN1 was downregulated in MM and that clustered regularly interspaced short palindr...

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Detalles Bibliográficos
Autores principales: Kong, Yuanyuan, Hu, Liangning, Lu, Kang, Wang, Yingcong, Xie, Yongsheng, Gao, Lu, Yang, Guang, Xie, Bingqian, He, Wan, Chen, Gege, Wu, Huiqun, Wu, Xiaosong, Zhan, Fenghuang, Shi, Jumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698482/
https://www.ncbi.nlm.nih.gov/pubmed/31423010
http://dx.doi.org/10.1038/s41419-019-1854-0