A versatile endosome acidity-induced sheddable gene delivery system: increased tumor targeting and enhanced transfection efficiency

BACKGROUND: Polycation carriers show great foreground in the developing efficient and safe gene delivery; nevertheless, they are cytotoxic and unstable in vivo because of the excess cationic charge. PEGylation improves the biocompatibility and stability of polycation, whereas PEGylation restrains th...

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Detalles Bibliográficos
Autores principales: Zhao, Ming, Li, Ji, Ji, Hongrui, Chen, Dawei, Hu, Haiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698616/
https://www.ncbi.nlm.nih.gov/pubmed/31616142
http://dx.doi.org/10.2147/IJN.S215250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698616/
https://www.ncbi.nlm.nih.gov/pubmed/31616142
http://dx.doi.org/10.2147/IJN.S215250

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