Cargando…
A versatile endosome acidity-induced sheddable gene delivery system: increased tumor targeting and enhanced transfection efficiency
BACKGROUND: Polycation carriers show great foreground in the developing efficient and safe gene delivery; nevertheless, they are cytotoxic and unstable in vivo because of the excess cationic charge. PEGylation improves the biocompatibility and stability of polycation, whereas PEGylation restrains th...
Autores principales: | Zhao, Ming, Li, Ji, Ji, Hongrui, Chen, Dawei, Hu, Haiyang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698616/ https://www.ncbi.nlm.nih.gov/pubmed/31616142 http://dx.doi.org/10.2147/IJN.S215250 |
Ejemplares similares
-
A Valid Bisphosphonate Modified Calcium Phosphate-Based Gene Delivery System: Increased Stability and Enhanced Transfection Efficiency In Vitro and In Vivo
por: Zhao, Ming, et al.
Publicado: (2019) -
Sheddable Coatings for Long-Circulating Nanoparticles
por: Romberg, Birgit, et al.
Publicado: (2007) -
Acid-Sensitive Sheddable PEGylated PLGA Nanoparticles Increase the Delivery of TNF-α siRNA in Chronic Inflammation Sites
por: Aldayel, Abdulaziz M, et al.
Publicado: (2016) -
Design of Tumor Acidity-Responsive Sheddable Nanoparticles for Fluorescence/Magnetic Resonance Imaging-Guided Photodynamic Therapy
por: Fan, Feng, et al.
Publicado: (2017) -
pH-Triggered Sheddable Shielding System for Polycationic Gene Carriers
por: Xia, Jialiang, et al.
Publicado: (2016)