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Boundaries of eliminated heterochromatin of Tetrahymena are positioned by the DNA-binding protein Ltl1

During differentiation of the Tetrahymena thermophila somatic nucleus, its germline-derived DNA undergoes extensive reorganization including the removal of ∼50 Mb from thousands of loci called internal eliminated sequences (IESs). IES-associated chromatin is methylated on lysines 9 and 27 of histone...

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Detalles Bibliográficos
Autores principales: Jaspan, Vita N, Taye, Marta E, Carle, Christine M, Chung, Joyce J, Chalker, Douglas L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698652/
https://www.ncbi.nlm.nih.gov/pubmed/31194876
http://dx.doi.org/10.1093/nar/gkz504