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Evaluation of antiseizure drug efficacy and tolerability in the rat lamotrigine‐resistant amygdala kindling model
OBJECTIVE: The lamotrigine‐resistant amygdala kindling model uses repeated administration of a low dose of lamotrigine during the kindling process to produce resistance to lamotrigine, which also extends to some other antiseizure drugs (ASDs). This model of pharmacoresistant epilepsy has been incorp...
Autores principales: | Metcalf, Cameron S., Huff, Jennifer, Thomson, Kyle E., Johnson, Kristina, Edwards, Sharon F., Wilcox, Karen S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698678/ https://www.ncbi.nlm.nih.gov/pubmed/31440726 http://dx.doi.org/10.1002/epi4.12354 |
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