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Stability of an RNA•DNA–DNA triple helix depends on base triplet composition and length of the RNA third strand
Recent studies suggest noncoding RNAs interact with genomic DNA, forming an RNA•DNA–DNA triple helix that regulates gene expression. However, base triplet composition of pyrimidine motif RNA•DNA–DNA triple helices is not well understood beyond the canonical U•A–T and C•G–C base triplets. Using nativ...
Autores principales: | Kunkler, Charlotte N, Hulewicz, Jacob P, Hickman, Sarah C, Wang, Matthew C, McCown, Phillip J, Brown, Jessica A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698731/ https://www.ncbi.nlm.nih.gov/pubmed/31265072 http://dx.doi.org/10.1093/nar/gkz573 |
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