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Closing the DNA replication cycle: from simple circular molecules to supercoiled and knotted DNA catenanes

Due to helical structure of DNA, massive amounts of positive supercoils are constantly introduced ahead of each replication fork. Positive supercoiling inhibits progression of replication forks but various mechanisms evolved that permit very efficient relaxation of that positive supercoiling. Some o...

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Detalles Bibliográficos
Autores principales: Schvartzman, Jorge B, Hernández, Pablo, Krimer, Dora B, Dorier, Julien, Stasiak, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698734/
https://www.ncbi.nlm.nih.gov/pubmed/31276584
http://dx.doi.org/10.1093/nar/gkz586