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Closing the DNA replication cycle: from simple circular molecules to supercoiled and knotted DNA catenanes
Due to helical structure of DNA, massive amounts of positive supercoils are constantly introduced ahead of each replication fork. Positive supercoiling inhibits progression of replication forks but various mechanisms evolved that permit very efficient relaxation of that positive supercoiling. Some o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698734/ https://www.ncbi.nlm.nih.gov/pubmed/31276584 http://dx.doi.org/10.1093/nar/gkz586 |