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DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy

The DNA damage response network guards the stability of the genome from a plethora of exogenous and endogenous insults. An essential feature of the DNA damage response network is its capacity to tolerate DNA damage and structural impediments during DNA synthesis. This capacity, referred to as DNA da...

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Detalles Bibliográficos
Autores principales: Pilzecker, Bas, Buoninfante, Olimpia Alessandra, Jacobs, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698745/
https://www.ncbi.nlm.nih.gov/pubmed/31251805
http://dx.doi.org/10.1093/nar/gkz531