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DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy
The DNA damage response network guards the stability of the genome from a plethora of exogenous and endogenous insults. An essential feature of the DNA damage response network is its capacity to tolerate DNA damage and structural impediments during DNA synthesis. This capacity, referred to as DNA da...
Autores principales: | Pilzecker, Bas, Buoninfante, Olimpia Alessandra, Jacobs, Heinz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698745/ https://www.ncbi.nlm.nih.gov/pubmed/31251805 http://dx.doi.org/10.1093/nar/gkz531 |
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