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Noise-reducing optogenetic negative-feedback gene circuits in human cells
Gene autorepression is widely present in nature and is also employed in synthetic biology, partly to reduce gene expression noise in cells. Optogenetic systems have recently been developed for controlling gene expression levels in mammalian cells, but most have utilized activator-based proteins, neg...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698750/ https://www.ncbi.nlm.nih.gov/pubmed/31269201 http://dx.doi.org/10.1093/nar/gkz556 |