Integrative construction of regulatory region networks in 127 human reference epigenomes by matrix factorization

Despite large experimental and computational efforts aiming to dissect the mechanisms underlying disease risk, mapping cis-regulatory elements to target genes remains a challenge. Here, we introduce a matrix factorization framework to integrate physical and functional interaction data of genomic seg...

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Detalles Bibliográficos
Autores principales: Liu, Dianbo, Davila-Velderrain, Jose, Zhang, Zhizhuo, Kellis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698807/
https://www.ncbi.nlm.nih.gov/pubmed/31265076
http://dx.doi.org/10.1093/nar/gkz538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698807/
https://www.ncbi.nlm.nih.gov/pubmed/31265076
http://dx.doi.org/10.1093/nar/gkz538

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