Allosteric Effects between the Antibody Constant and Variable Regions: A Study of IgA Fc Mutations on Antigen Binding

Therapeutic antibodies have shifted the paradigm of disease treatments from small molecules to biologics, especially in cancer therapy. Despite the increasing number of antibody candidates, much remains unknown about the antibody and how its various regions interact. Recent findings showed that the...

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Detalles Bibliográficos
Autores principales: Su, Chinh Tran-To, Lua, Wai-Heng, Ling, Wei-Li, Gan, Samuel Ken-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698812/
https://www.ncbi.nlm.nih.gov/pubmed/31544872
http://dx.doi.org/10.3390/antib7020020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698812/
https://www.ncbi.nlm.nih.gov/pubmed/31544872
http://dx.doi.org/10.3390/antib7020020

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