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Therapeutic and Diagnostic Antibodies to CD146: Thirty Years of Research on Its Potential for Detection and Treatment of Tumors

CD146 (MCAM, MUC18, S-Endo1) is a transmembrane glycoprotein belonging to both CAM and mucin families. It exists as different splice variants and is cleaved from the membrane by metalloproteases to generate a soluble form. CD146 is expressed by numerous cancer cells as well as being one of the numer...

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Detalles Bibliográficos
Autores principales: Stalin, Jimmy, Nollet, Marie, Dignat-George, Françoise, Bardin, Nathalie, Blot-Chabaud, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698816/
https://www.ncbi.nlm.nih.gov/pubmed/31548532
http://dx.doi.org/10.3390/antib6040017