Structural Changes in Stx1 Engineering Monoclonal Antibody Improves Its Functionality as Diagnostic Tool for a Rapid Latex Agglutination Test

Stx1 toxin is one of the AB(5) toxins of Shiga toxin-producing Escherichia coli (STEC) responsible for foodborne intoxication during outbreaks. The single-chain variable fragment (scFv) is the most common recombinant antibody format; it consists of both variable chains connected by a peptide linker...

Descripción completa

Detalles Bibliográficos
Autores principales: Luz, Daniela, Shiga, Emerson A., Chen, Gang, Quintilio, Wagner, Andrade, Fernanda B., Maranhão, Andrea Q., Caetano, Bruna A., Mitsunari, Thaís, Silva, Míriam A., Rocha, Letícia B., Moro, Ana M., Sidhu, Sachdev S., Piazza, Roxane M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698835/
https://www.ncbi.nlm.nih.gov/pubmed/31544861
http://dx.doi.org/10.3390/antib7010009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698835/
https://www.ncbi.nlm.nih.gov/pubmed/31544861
http://dx.doi.org/10.3390/antib7010009

Ejemplares similares