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In-Depth Comparison of Lysine-Based Antibody-Drug Conjugates Prepared on Solid Support Versus in Solution

Antibody drug conjugates are a rapidly growing form of targeted chemotherapeutics. As companies and researchers move to develop new antibody–drug conjugate (ADC) candidates, high-throughput methods will become increasingly common. Here we use advanced characterization techniques to assess two trastu...

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Detalles Bibliográficos
Autores principales: Arlotta, Keith J., Gandhi, Aditya V., Chen, Hsiao-Nung, Nervig, Christine S., Carpenter, John F., Owen, Shawn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698837/
https://www.ncbi.nlm.nih.gov/pubmed/31544859
http://dx.doi.org/10.3390/antib7010006