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In-Depth Comparison of Lysine-Based Antibody-Drug Conjugates Prepared on Solid Support Versus in Solution
Antibody drug conjugates are a rapidly growing form of targeted chemotherapeutics. As companies and researchers move to develop new antibody–drug conjugate (ADC) candidates, high-throughput methods will become increasingly common. Here we use advanced characterization techniques to assess two trastu...
Autores principales: | Arlotta, Keith J., Gandhi, Aditya V., Chen, Hsiao-Nung, Nervig, Christine S., Carpenter, John F., Owen, Shawn C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698837/ https://www.ncbi.nlm.nih.gov/pubmed/31544859 http://dx.doi.org/10.3390/antib7010006 |
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