Asymmetric Fc Engineering for Bispecific Antibodies with Reduced Effector Function

Asymmetric bispecific antibodies are a rapidly expanding therapeutic antibody class, designed to recognize two different target epitopes concurrently to achieve novel functions not available with normal antibodies. Many therapeutic designs require antibodies with reduced or silenced effector functio...

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Detalles Bibliográficos
Autores principales: Escobar-Cabrera, Eric, Lario, Paula, Baardsnes, Jason, Schrag, Joseph, Durocher, Yves, Dixit, Surjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698841/
https://www.ncbi.nlm.nih.gov/pubmed/31548523
http://dx.doi.org/10.3390/antib6020007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698841/
https://www.ncbi.nlm.nih.gov/pubmed/31548523
http://dx.doi.org/10.3390/antib6020007

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