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Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning
Membrane proteins are attractive targets for monoclonal antibody (mAb) discovery and development. Although several approved mAbs against membrane proteins have been isolated from phage antibody libraries, the process is challenging, as it requires the presentation of a correctly folded protein to sc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698842/ https://www.ncbi.nlm.nih.gov/pubmed/31548525 http://dx.doi.org/10.3390/antib6030010 |