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Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning

Membrane proteins are attractive targets for monoclonal antibody (mAb) discovery and development. Although several approved mAbs against membrane proteins have been isolated from phage antibody libraries, the process is challenging, as it requires the presentation of a correctly folded protein to sc...

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Detalles Bibliográficos
Autores principales: Alfaleh, Mohamed A., Jones, Martina L., Howard, Christopher B., Mahler, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698842/
https://www.ncbi.nlm.nih.gov/pubmed/31548525
http://dx.doi.org/10.3390/antib6030010