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Controlling the Glycosylation Profile in mAbs Using Time-Dependent Media Supplementation
In order to meet desired drug product quality targets, the glycosylation profile of biotherapeutics such as monoclonal antibodies (mAbs) must be maintained consistently during manufacturing. Achieving consistent glycan distribution profiles requires identifying factors that influence glycosylation,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698858/ https://www.ncbi.nlm.nih.gov/pubmed/31544854 http://dx.doi.org/10.3390/antib7010001 |