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Controlling the Glycosylation Profile in mAbs Using Time-Dependent Media Supplementation

In order to meet desired drug product quality targets, the glycosylation profile of biotherapeutics such as monoclonal antibodies (mAbs) must be maintained consistently during manufacturing. Achieving consistent glycan distribution profiles requires identifying factors that influence glycosylation,...

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Detalles Bibliográficos
Autores principales: Radhakrishnan, Devesh, Robinson, Anne S., Ogunnaike, Babatunde A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698858/
https://www.ncbi.nlm.nih.gov/pubmed/31544854
http://dx.doi.org/10.3390/antib7010001