Cargando…
Controlling the Glycosylation Profile in mAbs Using Time-Dependent Media Supplementation
In order to meet desired drug product quality targets, the glycosylation profile of biotherapeutics such as monoclonal antibodies (mAbs) must be maintained consistently during manufacturing. Achieving consistent glycan distribution profiles requires identifying factors that influence glycosylation,...
Autores principales: | Radhakrishnan, Devesh, Robinson, Anne S., Ogunnaike, Babatunde A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698858/ https://www.ncbi.nlm.nih.gov/pubmed/31544854 http://dx.doi.org/10.3390/antib7010001 |
Ejemplares similares
-
Controllability Analysis of Protein Glycosylation in Cho Cells
por: St. Amand, Melissa M., et al.
Publicado: (2014) -
SEPPA-mAb: spatial epitope prediction of protein antigens for mAbs
por: Qiu, Tianyi, et al.
Publicado: (2023) -
Glycosylation characterization of therapeutic mAbs by top- and middle-down mass spectrometry
por: Tran, Bao Quoc, et al.
Publicado: (2015) -
Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs
por: Fusco, Marnie L., et al.
Publicado: (2015) -
The Different Colors of mAbs in Solution
por: Ambrogelly, Alexandre
Publicado: (2021)