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Antibodies and Derivatives Targeting DR4 and DR5 for Cancer Therapy

Developing therapeutics that induce apoptosis in cancer cells has become an increasingly attractive approach for the past 30 years. The discovery of tumor necrosis factor (TNF) superfamily members and more specifically TNF-related apoptosis-inducing ligand (TRAIL), the only cytokine of the family ca...

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Detalles Bibliográficos
Autores principales: Dubuisson, Agathe, Micheau, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698863/
https://www.ncbi.nlm.nih.gov/pubmed/31548531
http://dx.doi.org/10.3390/antib6040016