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Comparing Within- and Between-Family Polygenic Score Prediction
Polygenic scores are a popular tool for prediction of complex traits. However, prediction estimates in samples of unrelated participants can include effects of population stratification, assortative mating, and environmentally mediated parental genetic effects, a form of genotype-environment correla...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698881/ https://www.ncbi.nlm.nih.gov/pubmed/31303263 http://dx.doi.org/10.1016/j.ajhg.2019.06.006 |