Urolithin A‐activated autophagy but not mitophagy protects against ischemic neuronal injury by inhibiting ER stress in vitro and in vivo

AIM: Mitochondrial autophagy (mitophagy) clears damaged mitochondria and attenuates ischemic neuronal injury. Urolithin A (Uro‐A) activates mitophagy in mammal cells and Caenorhabditis elegans. We explored neuroprotection of Uro‐A against ischemic neuronal injury. METHODS: Mice were subjected to mid...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahsan, Anil, Zheng, Yan‐Rong, Wu, Xiao‐Li, Tang, Wei‐Dong, Liu, Meng‐Ru, Ma, Shi‐Jia, Jiang, Lei, Hu, Wei‐Wei, Zhang, Xiang‐Nan, Chen, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698978/
https://www.ncbi.nlm.nih.gov/pubmed/30972969
http://dx.doi.org/10.1111/cns.13136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698978/
https://www.ncbi.nlm.nih.gov/pubmed/30972969
http://dx.doi.org/10.1111/cns.13136

Ejemplares similares