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Gene Families, Epistasis and the Amino Acid Preferences of Protein Homologs

In order to preserve structure and function, proteins tend to preferentially conserve amino acids at particular sites along the sequence. Because mutations can affect structure and function, the question arises whether the preference of a protein site for a particular amino acid varies between prote...

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Detalles Bibliográficos
Autor principal: Ferrada, Evandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698995/
https://www.ncbi.nlm.nih.gov/pubmed/31452598
http://dx.doi.org/10.1177/1176934319870485