Improving the anticancer effect of afatinib and microRNA by using lipid polymeric nanoparticles conjugated with dual pH-responsive and targeting peptides

BACKGROUND: The emergence of resistance to chemotherapy or target therapy, tumor metastasis, and systemic toxicity caused by available anticancer drugs hamper the successful colorectal cancer (CRC) treatment. The rise in epidermal growth factor receptor (EGFR; human epidermal growth factor receptor...

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Detalles Bibliográficos
Autores principales: Hong, Shu-Ting, Lin, Huaching, Wang, Chen-Shen, Chang, Chih-Hsien, Lin, Anya Maan-Yuh, Yang, James Chih-Hsin, Lo, Yu-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699136/
https://www.ncbi.nlm.nih.gov/pubmed/31426807
http://dx.doi.org/10.1186/s12951-019-0519-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699136/
https://www.ncbi.nlm.nih.gov/pubmed/31426807
http://dx.doi.org/10.1186/s12951-019-0519-6

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