Irradiated Bladder Cancer Cells Expressing both GM-CSF and IL-21 versus Either GM-CSF or IL-21 Alone as Tumor Vaccine in a Mouse Xenograft Model

Previous studies have established the efficacy of irradiated cancer cells overexpressing GM-CSF or IL-21 as a vaccine. Here we examined whether the vaccine efficacy was greater when both factors were overexpressed together. MB49 bladder cancer cells were transfected with expression plasmid pT7TS enc...

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Detalles Bibliográficos
Autores principales: Peng, Junming, Ye, Liefu, Li, Tao, Zhu, Qingguo, Guo, Jinan, Xiao, Kefeng, Wei, Yongbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699310/
https://www.ncbi.nlm.nih.gov/pubmed/31467912
http://dx.doi.org/10.1155/2019/8262989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699310/
https://www.ncbi.nlm.nih.gov/pubmed/31467912
http://dx.doi.org/10.1155/2019/8262989

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