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PEGylated Polyethylenimine Derivative-Mediated Local Delivery of the shSmad3 Inhibits Intimal Thickening after Vascular Injury

Intimal hyperplasia is a complex process which contributes to several clinical problems such as atherosclerosis and postangioplasty restenosis. Inhibition of Smad3 expression inhibits intimal thickening. Our previous study has modified biscarbamate cross-linked polyethylenimine derivative (PEI-Et) t...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Zhao, Danyang, Wei, Xiao, Ma, Lin, Sheng, Jing, Lu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699321/
https://www.ncbi.nlm.nih.gov/pubmed/31467913
http://dx.doi.org/10.1155/2019/8483765