Development and screening of brain-targeted lipid-based nanoparticles with enhanced cell penetration and gene delivery properties

BACKGROUND: The potential of gene therapy for treatment of neurological disorders can be explored using designed lipid-based nanoparticles such as liposomes, which have demonstrated ability to deliver nucleic acid to brain cells. We synthesized liposomes conjugated to cell-penetrating peptides (CPPs...

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Detalles Bibliográficos
Autores principales: dos Santos Rodrigues, Bruna, Lakkadwala, Sushant, Kanekiyo, Takahisa, Singh, Jagdish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699367/
https://www.ncbi.nlm.nih.gov/pubmed/31616141
http://dx.doi.org/10.2147/IJN.S215941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699367/
https://www.ncbi.nlm.nih.gov/pubmed/31616141
http://dx.doi.org/10.2147/IJN.S215941

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