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O-GlcNAc and EZH2-mediated epigenetic regulation of gene expression during consolidation of fear memories

O-GlcNAcylation of serine/threonine residues on target proteins occurs dynamically in postmitotic neurons of the hippocampus and may serve to control both the stability and activity of target proteins. Remarkably, the addition and removal of the O-GlcNAc posttranslational modifications are catalyzed...

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Detalles Bibliográficos
Autores principales: Butler, Anderson A., Sanchez, Richard G., Jarome, Timothy J., Webb, William M., Lubin, Farah D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699408/
https://www.ncbi.nlm.nih.gov/pubmed/31416910
http://dx.doi.org/10.1101/lm.049023.118