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Translating from cancer to the brain: regulation of protein synthesis by eIF4F

Formation of eukaryotic initiation factor 4F (eIF4F) is widely considered to be the rate-limiting step in cap-dependent translation initiation. Components of eIF4F are often up-regulated in various cancers, and much work has been done to elucidate the role of each of the translation initiation facto...

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Detalles Bibliográficos
Autores principales: Kats, Ilona R., Klann, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699409/
https://www.ncbi.nlm.nih.gov/pubmed/31416906
http://dx.doi.org/10.1101/lm.050047.119