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Polysomes identified by live imaging of nascent peptides are stalled in hippocampal and cortical neurites
In neurons, mRNAs can be repressed postinitiation and assembled into granules enabling the transport and later, regulated reactivation of the paused mRNAs. It has been suggested that a large percentage of transcripts in neuronal processes are stored in these stalled polysomes. Given this, it is pred...
Autores principales: | Langille, Jesse J., Ginzberg, Keren, Sossin, Wayne S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699411/ https://www.ncbi.nlm.nih.gov/pubmed/31416908 http://dx.doi.org/10.1101/lm.049965.119 |
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