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On the discovery of a potential survivin inhibitor combining computational tools and cytotoxicity studies

Survivin protein is a metalloprotein member of the inhibitors of apoptosis proteins family, involved in the regulation of programmed cell death. Due to the recent development of antitumor therapies having survivin as molecular target, several strategies to interfere with the expression or function o...

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Detalles Bibliográficos
Autores principales: Quispe, Patricia A., Lavecchia, Martin J., León, Ignacio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699424/
https://www.ncbi.nlm.nih.gov/pubmed/31440594
http://dx.doi.org/10.1016/j.heliyon.2019.e02238